The Customization of Commercial Base Rules in Dose Range Checking to Reduce Nuisance Alerts

Author: Hoang K. Nguyen

Primary Advisor: Anwar M. Sirajuddin, MBBS, MS (co-author)

Committee Members: Robert Murphy, MD (co-author); Kim Dunn, MD, PhD (co-author); Jiajie Zhang, PhD (co-author)

Masters thesis, The University of Texas School of Health Information Sciences at Houston.


Commercial base rules, given by third party vendors (Cerner), are used to check on medication order dosages. Often times however, these recommended dosages don’t fall within ranges of clinical practice which results in excessive “nuisance” alerts. This paper will describe the current state of dose range checking alerts and the changes that have been made to reduce it.