Nano Chemistry Service Center
The Nano Chemistry Service Center provides custom synthesis, labeling, and chemical coupling of DNA thioaptamers and nanoparticles. The Director and Lab Manager are both Ph.D. chemists with years of experience in DNA synthesis, especially the more difficult monothioated and dithioated DNA. In addition, they have conjugated numerous dyes, chelators, chemical linkers, and DNA spacers onto DNA. They have conjugated such DNA aptamers to liposomes, gold nanoparticles and mesoporous silicon particles for multi-stage vectors.
For more information or to schedule a meeting, please contact:
- Dr. David Volk, Director
David.Volk@uth.tmc.edu
(713) 500-2232 - Dr. Varatharasa Thiviyanathan, Manager
Varatharasa.Thiviyanathan@uth.tmc.edu
(713) 500-7558 - Scott Riley, Business Mgr.
John.S.Riley@uth.tmc.edu
(713) 500-3672NANO CHEMISTRY SERVICE CENTER PRICE SHEET
NBME – Nano Chemistry Service Center
Internal
External
DNA Synthesis and Purification
Monothioate Aptamer Synthesis
$ 300
$ 500
FPLC Aptamer Synthesis
$ 250
$ 250
5'-DNA Dyes and Linkers (per batch)
5'-Cy3 or 5'-Cy5 Labels
$ 495
$ 577
5'-Carboxy or Amino Linkers
$ 195
$ 390
5'-Chelator Labeling
$ 300
$ 400
5'-NIRdye800 Labeling
$ 1,200
$ 1,200
3'-DNA Dyes and Linkers (per oligonucleotide)
Class-I 3'-Dyes and 3'-Linkers
$ 75
$ 110
Class-II Specialty Dyes and Quenchers
$ 1,200
$ 1,400
Specialty Services and Chemistry
Chemical Conjugation Service (hourly)
$ 80
$ 110
X-Aptamer Synthesis*
$ 2,000
$ 2,000
Dithioate Aptamer Synthesis*
$ 2,000
$ 2,000
Aptamer Selection Service*
$ 15,000
$ 20,000
Nanoparticle Zeta Potential
$ 75
$ 125
Nanoparticle Production*
$ 500
$ 750
*Estimated cost, fee determined by project details
UTHealth provides a variety of service centers and core facilities to provide expert guidance and services to the UTHealth and wider Texas Medical Center community.
UTHEALTH SERVICE CENTERS AND CORE FACILITIES
SERVICE CENTRER LINKS
SERVICE CENTER DESCRIPTIONS
AFM and fluorescence imaging of tissue. Contact Dr. Ana-Maria Zaske for more information.
Statistical analysis of genetics, proteomics and metabolomic (metabonomic) data. Contact Co-Directors Dr. Jeffrey T. Chang or Dr. David Volk for more information.
Flow Cytometry detection and separation with detection of up to eight colors simultaneously. Contact Director Eva Sevick or Manager Dr. Amy Hazen for more information.
Histopathology Services and Dissections. Contact Director Eva Sevick or Manager Sarah Amra for more information.
Fluorescence and confocal microscopy and image analysis services. Contact Director Dr. Eva Zsigmond or Manager Dr. Zhengmei (Mei) Mao for more information.
Molecular diagnostic testing in a CLIA certified laboratory. MS-based clinical metabolites and Vitamin D, and discovery phase studies. Contact Director Dr. Kevin Rosenblatt for more information.
Aptamer development, synthesis, labeling, and conjugation. Particle characterization. Contact Director Dr. David Volk or Manager Dr. Varatharsa Thiviyanathan for more information.
Mass spectroscopy and affinity based proteomics services suitable for discovery or clinical research. Contact Dr. Kevin Rosenblatt for more information.
Production of transgenic /knockout mice, cryopreservation, and stem cell services. Contact Director Dr. Eva Zsigmond or Manager Aleksey Domozhirov for more information.
