The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases

Transgenic and Stem Cell Services

Transgenic and Stem Cell

The Transgenic Mouse and Stem Cells Core Facility was established in 1998 and since that time, it has generated over 700 new transgenic and knock-out mouse animal models for investigators from UTHealth, as well as for scientists from numerous other academic institutions.

The stem cell lines that have been derived in the laboratory are highly effective for the generation of knock-out/ knock-in mice and for cell differentiation studies. In addition to the production, cryopreservation and re-derivation of genetically-engineered mice and rats, the services of the facility also include gene targeting, derivation of new cell lines and intellectual/technical support in different aspects of microsurgery, cell culture and stem cells research.

SUMMARY OF SERVICES FORMS (PDF forms available below).  Click here to print Transgenic Flyer

SUMMARY OF SERVICES
Service Description

FEES
Prices Valid Through 8/31/2014

A.   MICROINJECTION    

UT
Houston Rates

Non UT
Houston
Rates

Transgenic Mice

$        4,070

$        5,088

Knock-out mice 129/SvIMJ ES cells (per day)

$        2,090

$        2,613

Knock-out mice C57BL/6ES cells (per day)

$        2,420

$        3,025

Knock-out mice BALB/c ES cells (per day)

$        2,420

$        3,025

B.  CRYOPRESERVATION

UT
Houston Rates

Non UT
Houston
Rates

Fertilized eggs

$           660

$           825

Sperm (per line, minimum of 3 lines)

$        1,100

$        1,375

Annually Renewable Storage Fee (1st line)
(each additional line $27.50)

$            55

$             69


C.  
 RE-DERIVATION

UT
Houston Rates

Non UT
Houston
Rates

Re-Derivation

$        1,155

$        1,444


D. 
ES CELL SERVICES

UT
Houston Rates

Non UT
Houston
Rates

Gene targeting and selection

$        8,250

$       10,313

Expansion and cryopreservation

$           715

$            894

Derivation of MEF feeder cells

$        2,200

$         2,750


E.   AVAILABLE CELL LINES

UT
Houston Rates

Non UT
Houston
Rates

Mouse ES cells (1 vial, passage 11) 129 /SVIM J

$           660

$            825

Mouse ES cells (1 vial, passage 11) C57/BL/6 or BALB/c

$           990

$         1,238

MEF feeder cells (passage 3) 129/SvIMJ or C57BL6

$           110

$            138

MEF feeder cells (passage 3) DR-4

$           110

$            138

Contacts:

Eva M. Zsigmond, PhD, Director
Phone: 713.500.2453 | Email: Eva.M.Zsigmond@uth.tmc.edu

Aleksey Domozhirov, Research Associate / Manager
Phone: 713.500.2452 | Email: Aleksey.Y.Domozhirov@uth.tmc.edu

UTHEALTH
The Brown Foundation Institute Of Molecular Medicine
1825 Pressler Street SRB 611
Houston, Texas 77030