The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases

IMM Core Facilities

Automated DNA Sequencing Core
Eric Boerwinkle, Ph.D.; 713.500.9803

An automated DNA sequencing core facility is accessible to all investigators. Protocols designed to make the core proficient in high through-put DNA sequencing have been implemented and the complete spectrum of DNA variation can be made available. Analytical methods have been developed so that analyses of these variant DNA sites may proceed in a logical manner. Finally, the staff of the core facility are developing novel experimental protocols to provide the most accurate data for analysis of DNA sequences necessary for the use of molecular biology techniques.

Protein Chemistry Core

The Protein Chemistry Core provides services to various research projects within the Brown Foundation Institute of Molecular Medicine, as well as to the UT-Houston Medical School. The core also provides service of IKAT and ITRAQ chemistry-based proteomics anqalysis. Services are provided on fee-per-analysis basis.

The core is equipped with state-of-the-art instrumentation, including mass spectrometers, automatic protein sequencer, high performance liquid chromatography system, circular dichroism spectropolarimeter, fast protein liquid chromatography system, spectrophotometer, triple dectector array light scattering and lyophylizers that are required for identification, purification and structure-function analysis of proteins.