Faculty and Research Interests
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FACULTY |
RESEARCH INTERESTS |
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Oncogenes in the behavior of cancer; Primary brain tumors |
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Germline development and Morphogenesis of oogenesis; RAS/ERK signaling pathways governing germ cell development; C. elegans genetics |
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Proteomics; Microarrays; Gene Expression Analyses |
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Human genetics; Genotype by environment interaction; Epidemiology; Heart disease; Lipid metabolism; Apolipoprotein genes; DNA variation |
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Program Director 2008-2010 |
RNA processing, RNA splicing and cancer; Familial endocrine neoplasia |
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Human population and molecular genetics; Retinitis pigmentosa; Mutation detection; Functional studies of genes and proteins causing inherited retinal diseases |
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Gene editing of stem cells; Stem cell biology; Gene therapy; Hematopoietic stem cells; Somatic reversion; Molecular genetics |
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Cell differentiation; Transcription factors; Chondrocytes; Osteoblasts |
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Genetics of cardiovascular disease; Stroke; Gene expression; Gene-environment interaction |
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Genetics of colorectal cancer; Modifier genes; Environmental factors; Hereditary nonpolyposis colorectal cancer (HNPCC) Peutz-Jeghers syndrome |
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Molecular evolution; Population genetics; Bioinformatics; Computational genomics |
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Molecular genetics and genomics of gastrointestinal neoplasia; Identification of molecular markers for application in screening, surveillance, diagnosis, prognosis, prediction of response and resistance to therapy, and therapeutic targets |
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Quantitative genetics; Genetics of common chronic disease; Genetic epidemiology; Diabetes among Mexican-Americans; Genome-wide approaches to identifying disease genes |
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Medical genetics; Chondrocyte biology; Nonsyndromic cleft lip and palate; Nonsyndromic clubfoot |
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Program Director 2006-2008 |
Molecular genetics; Genetics of common disease; Gene structure and expression in atherosclerosis |
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Human genetics; Cancer genetics; Familial cancer predisposition; Kidney development |
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Program Director 199-1998 Program Co-Director 2012 |
Tumor suppressor genes; Breast and pancreatic cancer; Cancer genetics; Biomarker Discovery for the Early Detection of Pancreatic Cancer |
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Human and molecular genetics; Cancer genetics; Neurogenetics; Genomics; Mouse Models |
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Eukaryotic DNA repair; Cell cycle checkpoints; Carcinogenesis |
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Genomic instability; DNA damage and replication checkpoint mechanisms; Mutagenesis; Mammalian DNA repair and recombination; Molecular genetics |
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Adult and embryonic stem cells; Neural/glial tumors; Transcriptional regulation; Chromatin; Mouse models |
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Germ Cell tumors, genetics susceptibility; mouse models |
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Genetics of vascular disease, aortic and cerebral aneurysms, proteomics |
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Genetic determinants of congenital malformations; Maternal genetic effects; gene-environment interactions; Statistical genetics |
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Human genetics; Genetic epidemiology; Cardiovascular disease; Statistical methodology |
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Genetic regulation; Chromosomal alterations; Malignant Transformation; Hematopoietic stem cell ; Mouse Models |
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Medical genetics; Molecular genetics of human disease; Tuberous sclerosis; Spina bifida |
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Genetic epidemiology; Computational biology; Bioinformatics; Data mining; Artificial intelligence; Machine learning; Molecular evolution; Phylogenetics |
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Statistical genetics; Human population genetics; Genetics of common diseases; Haplotype inference/modeling |
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Program Director 2012-Present |
Genetic regulation of mitosis and chromosomal instability in cancer; Development of early detection genomic biomarkers of cancer |
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Head and neck cancer epidemiology; Gene-gene and gene-environment interactions; Genomic imprinting; Genetic epidemiology of familial glioma; Haplotype reconstruction and analysis methods; Epidemiological methods; Genetic segregation and linkage analysis; Genome-wide Association Studies |
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Genetic Counseling; Inherited Genetic Disorders |
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Human cancer genetics; Genetic epidemiology |
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Developmental biology and genetics; Zebrafish; Mouse; Developmental neuroscience |
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Radiation-induced fibrosis; Genetic basis of tissue radiation sensitivity and fibrosis; Growth factors |
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Biomarkers of cancer; DNA repair and apoptosis; Molecular epidemiology; Cancer prevention |
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Bioinformatics; Statistical genetics; Mapping complex trait; Mapping QTL; Functional genomics; Human gene expression maps and gene expression databases; Genetic circuits |
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Computational genome biology; Gene expression microarray data modeling; Networks of gene expression regulation |
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Mechanisms of neuronal degenerative disorders; Huntington’s disease (HD); Parkinson’s disease (PD); Intracellular handling of neurotransmitter dopamine; Regulation of the formation of intracellular protein aggregates |
