Dr. Yeonseok Chung
The University of Texas Health Science Center at Houston
Institute of Molecular Medicine
Center for Immunology and Autoimmune Disease
- T cell differentiation by innate immune system
- Regulation of mucosal immunity
- Cytokines in inflammation and cancer
- Plasticity of T cell subset
- Cancer immunotherapy
- Transgenic/knockout animal model
The goal of my research is to understand the molecular and cellular mechanisms that control the development and progress of inflammation and cancer, with particular emphasis on the mucosal immune system. We use in vivo animal model systems to examine the biological function of T cell subsets and cytokines within the immune system. Presently our studies involve three areas of investigation: (i) Understanding the plasticity and antagonism of T cell immunity in mucosal area; (ii) Characterizing the function of IL-1 and IL-10 family cytokines in chronic inflammation and cancer; (iii) Development of a novel vaccine approach against cancer and infectious agents.
A tutorial in my laboratory will provide experience in molecular and cellular research in inflammation and cancer using current techniques of molecular biology, cell biology, animal disease models, and transgenic/knockout technology. In addition, the tutorial will focus on learning to think independently and to set up exciting, and medically relevant research projects.