Dr. Madeleine Duvic
The University of Texas M. D. Anderson Cancer Center
Department of Dermatology
- Translational research in the molecular pathogenesis and immunology of T cell mediated disorders (cutaneous lymphomas, psoriasis, alopecia areata) and skin cancers
- Clinical drug development for lymphoma, melanoma, and skin cancer involving retinoids, histone deacetylase inhibitors, targeted antibodies and fusion toxin
Objectives are  To understand the molecular mechanisms of cutaneous T-cell lymphomas (and other T-cell mediated diseases).  To develop FDA approved safe and effective therapies that modulate gene expression and induce T-cell apoptosis.
A tutorial in my laboratory would involve molecular biology techniques, tissue culture, gene modulation with siRNAs, immunology, immunohistochemistry, mouse tumor models, depending on the project selected.