Dr. Sattva S. Neelapu
The University of Texas M. D. Anderson Cancer Center
Department of Lymphoma and Myeloma
- Tumor immunology
- Cancer vaccines
- Novel tumor antigen discovery
- Adoptive T-cell therapy
- Immunological monitoring
The research in my laboratory is directed at identifying novel tumor-associated antigens in lymphoma and development of adoptive immunotherapeutic strategies for lymphoma. Tumor-specific T-cell lines and clones were generated from the tumor-infiltrating lymphocytes or peripheral blood of lymphoma patients. We are currently working to identify the antigens recognized by these T-cell clones using the tumor cDNA library expression cloning approach. We are also working to optimize the generation of tumor-specific T cell lines for adoptive T-cell therapy. The long-term goal of my research is to translate the discoveries in the laboratory to the clinic for active and passive immunotherapy of lymphoma patients.
A graduate student’s tutorial in my laboratory would involve research in tumor antigen discovery, immunological monitoring, tumor immunology, cellular immunology, and molecular immunology.
Program in Immunology