Dr. Ana M. Aparicio
The University of Texas MD Anderson Cancer Center
Department of Genitourinary Medical Oncology
The goal of our research is to understand epigenetic mechanisms involved in the pathogenesis of genitourinary malignancies, with a special interest in prostate cancer, to be able to target them with the new epigenetic therapies that are emerging. One of our main interests is to develop biomarkers that will permit the optimal application of the new epigenetic drugs in the treatment of solid tumors in general, and genitourinary
malignancies in particular. Current studies in our laboratory focus on the use of LINE methylation as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors and in developing an understanding at the molecular level of the different clinical phenotypes that prostate cancers exhibit.
A tutorial with us would provide experience with DNA and RNA extraction from human tissues, bisulfite conversion of DNA, PCR and related assays and Pyrosequencing.
Office: MDA CPB7.3512 (Unit 1374)
Title: Assistant Professor
M.D. - Universidad Autonoma de Madrid - 1995