Dr. Dean G. Tang
Regular Member
The University of Texas MD Anderson Cancer Center
Department of Molecular Carcinogenesis
The Virginia Harris Cockrell Cancer Research Center
My laboratory is located in Smithville, Texas, at UT Science Park
Research Interests:
- Cancer stem cells
- Stem cells
- Prostate cancer
The current focus of our lab research is to understand the cellular basis and molecular determinants of prostate cancer (PCa) cell heterogeneity. The laboratory currently has the following interconnected ongoing research projects.
1. Normal prostate stem/progenitor cells and involvement in tumorigenesis
2. Prostate CSCs in xenograft & patient tumors
3. Prostate CSC involvement in metastasis
4. Prostate CSC response to androgen deprivation & other therapeutics
5. Prostate CSC self-renewal: Role of Nanog
6. Prostate CSC epigenetic landscape
7. Prostate CSC regulation by miRNAs
8. Prostate CSC asymmetric cell division
9. Developing mAbs and drugs that specifically target prostate CSCs
These projects involve both human PCa and novel transgenic animal models. The ultimate goal of our research is to uncover the unique properties of prostate CSCs and design specific therapeutics to target them.
Publications
Lab Web Page
Program Affiliation:
Program in Molecular Carcinogenesis
Contact Information
Phone: 512.237.9575
Email: dtang@mdanderson.org
Office: MDA SPR (Unit 116)
Title: Professor
Education:
Ph.D. - Wayne State University - 1994
M.S. - Wuhan University School of Medicine - 1989
