Dr. Rick A. Wetsel
The University of Texas Health Science Center at Houston
Institute of Molecular Medicine
Center for Immunology and Autoimmune Diseases
- Seven-transmembrane G protein-coupled proinflammatory receptors
- Transgenic/knockout murine models
- Molecular genetics of inherited immunodeficiencies
The research in my laboratory is directed at delineating molecular mechanisms that mediate the inflammatory response as well as those that cause immune-dysfunction. Presently, our studies involve four areas of investigation; 1) receptor-mediated chemotaxis and adhesion of inflammatory cells; 2) molecular regulation of the inflammatory response; 3) molecular genetic basis of immune deficiencies; and 4) development and study of murine models of human autoimmune diseases. Many of these investigations involve studies of the complement system.
A tutorial in my laboratory would provide experience in molecular research in immunology and inflammation using modern techniques of molecular biology, cell biology, protein chemistry, and transgenic/knockout technology.