Dr. Jack C. Waymire
Regular Member
The University of Texas Health Science Center at Houston
Medical School
Department of Neurobiology and Anatomy
Research Interests:
- Neuronal regulation of neurotransmitter differentiation, biochemistry and secretory function in catecholamine neurotransmitter secreting cells
The long-range objective of research in Dr. Waymire's laboratory is to determine the cellular and molecular changes required to establish catecholamine neurotransmitter secretion from adult and various stem cell lines. The goals of this work is to establish the underlying molecular and cellular processes responsible for the catecholamine phenotype and modulation of catecholamine biosynthesis and secretion within these cells. His laboratory accomplishes this studies to understand how tyrosine hydroxylase, the enzyme that regulates catecholamine biosynthesis, and several other catecholamine-specific proteins are regulated. His laboratory is currently working to understand: 1) the role of the phosphorylation 2) the role of the transcription and 3) the role of mRNA stabilization in modulating these catecholamine specific proteins.
A tutorial in Dr. Waymire's laboratory will provide experience in protein purification, HPLC peptide purification, protein phosphorylation, immunoblotting, mRNA analysis, in situ protein expression, mutagenesis, enzyme assays, and primary tissue culture.
Publications
Program Affiliations:
Program in Cell and Regulatory Biology (Pharmacology and Physiology Tracks)
Program in Neuroscience
Contact Information
Phone: 713.500.5620
Email: Jack.C.Waymire@uth.tmc.edu
Office: MSB 7.252
Title: Professor
Education:
Ph.D. - Ohio State University - 1969
