Dr. Magnus Hook
Texas A&M Health Science Center
Institute of Biosciences and Technology
Center for Infectious and Inflammatory Diseases
- Molecular mechanisms of infectious disease
- Protein structures and interactions
- Drug development
The research in our laboratory is focused on determining the molecular pathogenesis of infections and inflammatory diseases. We are interested in two key areas in the pathogenic process: microbial adherence to host tissue and microbial evasion of host defense systems. We seek to identify the molecules involved in these processes, characterize the interactions in submolecular detail using detailed biochemical methods, and articulate molecular hypotheses describing the disease process. These hypotheses are then evaluated in model systems and compared to the clinical findings in human disease. Ultimately, we seek to translate our research findings into new or improved strategies to prevent and treat infectious diseases.