Dr. Suyun Huang
The University of Texas MD Anderson Cancer Center
Department of Neurosurgery
- Molecular mechanisms of tumor metastasis
- Transcriptional factors
- Molecular diagnosis and therapy
My research focuses on the molecular regulation of gene expression that play critical roles in tumor angiogenesis, invasion and metastasis. I am currently investigating the molecular determinants of brain metastasis (from other organs) and primary brain tumor (glioma). Specifically, I am studying the transcriptional regulation of genes that play critical roles in tumor angiogenesis, invasion and metastasis, e.g., VEGF, bFGF and MMPs. The important role of transcription factors, such as NF- k B , Stat3 and FoxM1, in the regulation the expression of these genes is being studied. The effects of altered activation of these transcription factors on tumor angiogenesis, invasion and metastasis are also being examined on animal models. These studies contributeto better understanding of molecular mechanism of tumor metastasis, and provide insights for development of potential prognostic and therapeutic strategies against metastasis.
A tutorial in my laboratory would provide experience with cell culture, animal models, and basic and advanced molecular biology in gene expression and regulation of tumor angiogenesis and metastasis.
Program in Cancer Biology
Office: MDA BSRB S5.8116B (Unit 1004)
Title: Associate Professor
M.D. - Anhui Medical University - 1985
Ph.D. - The University of Texas Graduate School of Biomedical Sciences at Houston - 1997