Dr. Paul J. Chiao
Regular Member
The University of Texas MD Anderson Cancer Center
Department of Molecular and Cellular Oncology
Research Interests:
- The mechanism for cytokine-induced biphasic activation of Rel/NF-kappaB
- The signaling pathways for growth factor-induced Rel/NF-kappaB activation in cancers
- The mechanism by which Rel/NF-kappaB regulates both antiapoptotic and proapoptotic responses
- The role of NF-kB in the development of tumors and metastasis
The goal of my research is to understand the role of oncogenes and tumor suppressor genes in the development of tumors and metastasis. A tutorial in my laboratory would provide a learning experience in designing experiments and testing hypothesis using various techniques such as DNA and RNA isolation and purification, construction of expression vectors, transfection, inhibition of gene expression by small interfering RNA, kinase assay, electrophoretic mobility shift assay, reporter gene assays, Western, Southern, Northern blot analyses, PCR and protein purification.
Publications
Program Affiliation:
Program in Cancer Biology
Contact Information
Phone: 713.794.1030
Email: pjchiao@mdanderson.org
Office: MDA Y8.6085 (Unit 108)
Title: Professor
Education:
Ph.D. - The University of Texas Graduate School of Biomedical Sciences at Houston - 1991
