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GS14 1021   Topics in the Neurobiology of Disease

Savitz, Sean, Coordinator. One semester hour. Fall annually.

This course addresses the emerging role of stem cells and other regenerative strategies as potential, novel investigational treatments for acute neurological disorders and neurodegenerative diseases.    An introduction to the broad topic of stem cells and other cellular therapies will be explored including neural stem cells, embryonic stem cells, induced pluripotent stem cells, and adult cell types.  We will define mechanisms of action of injury and recovery, address translational barriers to the successful adoption of cell therapies from animals to patients, and explore the therapeutic challenges of applying regenerative medicine to neurological disease.  Specific lecture topics will include stroke, traumatic brain Injury, spinal cord injury, ALS, and Alzheimer’s disease.  In addition, alternative strategies to stimulate endogenous repair mechanisms after brain damage will also be discussed.  

This course is open to graduate students, medical students, and postdoctoral fellows.